Dendritic Cells Negative Control of CD8 T Cell Priming by Type I IFN-Induced, NKT Cell-Mediated
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منابع مشابه
Type I IFN-induced, NKT cell-mediated negative control of CD8 T cell priming by dendritic cells.
We investigated the negative effect of type I IFN (IFN-I) on the priming of specific CD8 T cell immunity. Priming of murine CD8 T cells is down-modulated if Ag is codelivered with IFN-I-inducing polyinosinic:polycytidylic acid (pI/C) that induces (NK cell- and T/B cell-independent) acute changes in the composition and surface phenotype of dendritic cells (DC). In wild-type but not IFN-I recepto...
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تاریخ انتشار 2008